University of California (Irvine) Program

The Division of Hematology and Oncology at the University of California, Irvine (UCI) School of Medicine offers a comprehensive fellowship program that spans three years and leads to board eligibility in both hematology and medical oncology through the American Board of Internal Medicine (ABIM). Every year, four fellows are accepted into the program, which is conducted in collaboration with two primary training sites: the UCI Medical Center, which includes the NCI-designated Chao Family Comprehensive Cancer Center, and the Tibor Rubin VA Medical Center in Long Beach.

This fellowship is carefully structured to cultivate future clinical investigators with a strong foundation in patient care, alongside a rigorous understanding of clinical trials and translational research. The educational approach heavily emphasizes mentorship, particularly during an 18-month dedicated research rotation that allocates approximately 70% of time towards research along with 10% to 20% in the clinical setting with the subspecialty mentor. Fellows are expected to design and submit a clinical trial protocol under guidance of their research mentor as a graduation requirement. This focus has resulted in many graduates pursuing successful academic careers or joining reputable group practices.

Throughout the first year of training, fellows identify a panel of outpatients to follow throughout their fellowship, gaining in-depth exposure to solid tumor oncology and general hematology under faculty supervision. Foundational concepts are prioritized, covering pathophysiological processes, clinical manifestations, diagnostic methodologies, and standard or experimental therapeutic modalities. Inpatient clinical experience allows for comprehensive consultative care across a diverse patient population, supplemented by daily formal teaching sessions and didactic lectures focusing on ongoing clinical trials and correlative studies.

Fellows also engage in sectors of quality improvement, wellness initiatives, and various academic activities including Journal Club, morbidity and mortality conferences, and multiple disease-specific tumor boards that are scheduled weekly. Over the course of the second and third years, fellows pursue longitudinal research projects with dedicated protected time, designed to cultivate a robust research portfolio.

UCI, recognized as a major NIH-funded institution, offers a multitude of research opportunities, from basic molecular biology to translational clinical trials. Its comprehensive research environment enables fellows to cultivate their research skills effectively. During dedicated research rotations, fellows receive specialized training in varied clinical hematology laboratory experiences necessary for preparing papers for presentation and publication.

Eligibility requirements for this fellowship include completion of a three-year ACGME-approved residency in internal medicine, and candidates must demonstrate a keen interest in the fields of hematology and oncology. Only U.S. citizens, permanent residents, or individuals holding a J-1 visa with ECFMG sponsorship are eligible to apply. Furthermore, obtaining a valid California medical license prior to commencing the fellowship is mandatory, which can entail a process of several months for international medical graduates.

,The application process requires submission through the Electronic Residency Application Service (ERAS), including personal statements, letters of recommendation, transcripts, and medical school credentials. Applications should be submitted promptly to ensure consideration within the program's set timelines; late applications may not be accepted.

UCI's fellowship program also promotes a culture of diversity and collaboration, reflecting the institution's commitment to inclusive excellence and support. The fellowship is housed within a division that encompasses over 50 clinician-scientists, laboratory-based investigators, and advanced practitioners who work together under the auspices of the NCI-designated center, fostering a broad spectrum of fellowship experiences.

For visa support, UCI can sponsor J-1 visas for eligible candidates. Those who are U.S. citizens or permanent residents have other pathways without the need for sponsorship.

Finally, UCI's Hematology and Oncology fellowship program is competitive with various applicants from diverse backgrounds. It actively seeks out promising candidates who demonstrate a strong potential for success in both patient care and research. The program maintains an inclusive approach towards DOs and International Medical Graduates (IMGs), facilitating opportunities for these applicants while upholding rigorous selection standards.