Duke University Hospital Program

The Medical Biochemical Genetics Fellowship program at Duke University is a one-year program designed to cultivate skilled clinicians and researchers in the field of medical biochemical genetics. This fellowship is part of the Division of Medical Genetics in the Duke University Department of Pediatrics and is accredited by the Accreditation Council for Graduate Medical Education (ACGME).

This program is specifically targeted at physicians who hold a valid, unrestricted license to practice medicine in the United States or Canada and have completed an ACGME-accredited residency in Medical Genetics and Genomics or a combined residency program endorsed by the American Board of Medical Genetics and Genomics (ABMGG). The commitment to excellence in clinical practice and research distinguishes the program as a center of recognition both nationally and globally.

The division is a vital center for the diagnosis, treatment, and research of biochemical genetic disorders. It collaborates with the Mass Spectrometry facility and the Glycogen Storage Disease Laboratory; together, these resources form a comprehensive Metabolic Clinic. This unit particularly focuses on treating known or suspected Inborn Errors of Metabolism (IEM), emphasizing disorders concerning carbohydrate/glycogen metabolism and Lysosomal Storage Disorders (LSDs).

Training and Clinical Experience

The fellowship provides fellows with clinical and laboratory training concerning biochemical genetic disorders. Trainees manage acute metabolic decompensations with guidance from experienced attending physicians who collaborate with specialists across various fields. This cross-disciplinary interaction is invaluable as fellows navigate the intricate manifestations of IEM.

Moreover, the Metabolic Clinic serves as a model for future healthcare leaders, illustrating how to establish comprehensive care and research in complex genetic diseases in their own practices.

The program is recognized for its progressive approach to clinical training, which is bolstered further by several internationally acknowledged translational research initiatives. These research programs enjoy funding from a combination of private, corporate, and governmental sources. Research projects often explore enzyme replacement therapy (ERT) for LSDs, gene therapy, and thorough investigations into Glycogen Storage Diseases (GSDs), underscoring the research component's innovation.

Program Overview

Each year, the Medical Biochemical Genetics Fellowship offers one position. Currently, there are two fellows in the program. The training extends over the span of one year, providing a deep dive into the unique aspects of biochemical genetics.

Application Process

To apply for the Medical Biochemical Genetics Fellowship, candidates are required to submit a curriculum vitae (CV), a personal statement, and three letters of recommendation addressed to the program director. Those who have obtained their graduate degree outside the U.S. must include a Credential Evaluation letter from the ABMGG. The fellowship promotes an inclusive practice, considering applications without bias regarding race, religion, gender, or national origin.

Visa Support and Competitiveness

The Medical Biochemical Genetics Fellowship at Duke University is committed to supporting international candidates through various visa types suitable for training, such as the J-1 visa for exchange visitors. The program is known to be competitive, welcoming applicants with diverse backgrounds, including those holding DO degrees and IMGs.

Unique Aspects of the Program

In addition to robust clinical experiences, the fellows are encouraged to participate actively in research output and to engage with national and international conferences. This involvement ensures that fellows stay abreast of developments in the fast-evolving field of medical biochemical genetics.

Current Fellows and Faculty

The dynamic environment is further enriched by the work of current fellows, who actively contribute to ongoing research projects, and the diverse faculty engaged in various subspecialties of pediatrics and genetics. This diversity among faculty fosters an innovative culture aimed at solving complex genetic disorders.

The program remains dedicated to attracting highly qualified individuals who value diverse perspectives and believe in collaborative excellence, ensuring their training meets the global standards of medical education.