University of California (San Francisco) Program

The University of California, San Francisco (UCSF) Program in Molecular Genetic Pathology Fellowship is a one-year, ACGME-accredited program offered by the Departments of Anatomic Pathology and Laboratory Medicine. This fellowship aims to cultivate independent laboratory directors and future academic leaders within the field of molecular genetic pathology. The training provided is both generalized and customizable, allowing fellows to focus on specific areas of interest while working closely with faculty mentors throughout the year.

The curriculum encompasses a variety of key topics, including cancer genetics (encompassing both solid tumors and hematopathology), inherited diseases, infectious diseases, pharmacogenomics, and cytogenetics. Fellows will engage actively in clinical practice within the Medical Genetics Clinics, gaining hands-on experience in performing molecular testing, interpreting and reporting test results, developing and validating new testing methodologies, as well as managing clinical molecular pathology laboratories. The fellowship program emphasizes the financial considerations associated with genetic and genomic testing, integrating these efforts with the clinical genetics team, which includes physicians and counselors.

Throughout the fellowship, trainees will immerse themselves in the practical use of next-generation sequencing (NGS), array technologies, and low signal detection techniques, such as circulating nucleic acid detection. Fellows will rotate through four major testing laboratories, providing a flexible training schedule that accommodates educational opportunities across different clinical focuses throughout the year. A regular schedule of conferences, including various patient management meetings and a symposium series led by the UCSF Institute of Human Genetics, facilitates ongoing education and exposure to global leaders in the field.

Fellows are expected to contribute to at least one academic research project during their training, alongside involvement in test validation projects and lab management training. For those seeking more concentrated research experience, a second year of fellowship may be arranged to allow deeper engagement in specific interests. It is advised that applicants discuss their schedules to accommodate this potential second year, particularly in coordination with any other UCSF fellowships.

Application Requirements

For eligible candidates, the UCSF program requires completion of at least one year of training in an ACGME-accredited AP, CP, or combined AP/CP residency program, and they must be in good standing at the time of application. The fellowship program encourages applications from individuals whose backgrounds in teaching, research, or community service align with the program's commitment to diversity and excellence. Non-U.S. citizens must possess either a Permanent Resident Card or a suitable educational visa prior to starting the program. The program sponsors J1 visas upon selection, and candidates must acquire an unrestricted medical license from the Medical Board of California before the start date.

Certification and Fellowship Details

Candidates interested in pursuing board certification in molecular genetic pathology (MGP) must either be certified in AP/CP, AP, or CP, or hold certification from the American Board of Medical Genetics and Genomics (ABMGG). The fellowship at UCSF meets the training requirements necessary for this certification. The financial remuneration for fellows during this one-year fellowship program corresponds to the PGY-5 level.

Competitive Nature and Diversity

The Molecular Genetic Pathology Fellowship at UCSF is highly competitive, and application materials will include a standardized fellowship application, a curriculum vitae, a personal statement of interest, three letters of recommendation in PDF format, and a photo of the applicant. The fellowship program maintains a firm commitment to promoting diversity and inclusion, actively seeking candidates from diverse backgrounds and experiences.

Timeline and Additional Information

Applications for the fellowship are typically accepted from Summer to Fall 2024 for appointments scheduled in July 2026. The application process will include virtual interviews, ranking opportunities, and ultimately culminate in designated Match Day activities that follow the timeline established by the NRMP. For ongoing updates, interested applicants are encouraged to refer to the UCSF program's faculty web pages and resources for detailed information on application protocols and requirements.