The Laboratory Genetics and Genomics fellowship trains fellows to direct and interpret clinical cytogenetic and molecular genetic tests relevant to the diagnosis and management of human genetic diseases. Diplomates certified in Laboratory Genetics and Genomics act as directors and/or consultants in laboratory diagnoses for a broad range of inherited and acquired conditions, including those of Mendelian and chromosomal origin. The fellowship has combined the elements of the previous clinical cytogenetics and clinical molecular genetics fellowships into one new fellowship in laboratory genetics and genomics. This program aims to prepare trainees for the evolving landscape of laboratory genetics.
The training includes rotations through molecular diagnostics, cytogenetics and genomics, biochemical genetics, and clinical genetics in the laboratories and clinics of Barnes Jewish Hospital (BJH) and Washington University School of Medicine. Facilities for this training are state-of-the-art and located within the medical campus, focusing on various specimen types, including prenatal, neonatal, pediatric, adult, and oncology samples. The Department of Pathology and Immunology, along with the BJH labs, handles testing for these specimens. The curriculum is meticulously designed to cover all aspects of laboratory genetics and genomics, assuring that fellows develop the necessary skills to effectively supervise and direct operations.
Among the primary educational goals, fellows are expected to gain expertise in selecting appropriate technologies for diagnosing human diseases and are trained in interpreting a broad spectrum of genetic diagnostic tests. These include methodologies assessing chromosomal aneuploidies, structural changes, single nucleotide variants, and genomic copy number variations. Furthermore, fellows will learn to analyze diverse tissue types such as tumors, cell-free DNA, and bone marrow to integrate clinical data with laboratory results, thus fostering a comprehensive understanding of genetic health.
Training Sites
The program takes place in advanced facilities at key institutions: Washington University School of Medicine, Barnes-Jewish Hospital, and St. Louis Children’s Hospital. The Laboratory Genetics and Genomics site is situated in a modern building within the CORTEX District, a hub that promotes research and technological exchange, showcasing the program's commitment to cutting-edge facilities.
Program Requirements and Application Process
Candidates for this fellowship must possess a doctoral degree (PhD or MD) in biological or biochemical sciences or medicine. The application process for the upcoming fellowship positions typically opens on a predetermined schedule, reflecting anticipation for the next cohort of fellows.
Visa Support and Competitiveness
The program supports various visa types for international applicants, ensuring that candidates from diverse backgrounds can engage in the fellowship. The program is designed to be highly competitive, beneficial for both US-based and international medical graduates, including those with DO degrees.
Unique Aspects of the Program
Fellows in this program benefit from a comprehensive educational structure that encourages integrating clinical data with molecular diagnostics, fostering collaborative efforts across various specialties. Daily teaching conferences augment the hands-on training received in laboratories, ensuring that fellows are not only skilled technicians but also effective communicators of complex genetic information to referring clinicians and patients.
The hands-on training supplemented with case presentations and regular conferences promotes an interactive educational environment, enhancing the fellows' professional development and preparedness for future roles in laboratory genetics and genomics.
Additional Resources
The program offers several resources for well-being support, emphasizing the overall welfare of trainees through wellness initiatives and counseling services. This focus on well-being ensures that fellows remain in optimal health and are equipped to handle the rigors of their training.
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St. Louis, MO
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