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Should I Major in Biology, Chemistry, or Something Else as a Pre‑Med?

December 31, 2025
13 minute read

Pre-med student choosing between biology, chemistry, and other majors -  for Should I Major in Biology, Chemistry, or Somethi

The biggest myth in pre‑med is that you have to major in biology or chemistry to get into medical school. You don’t.

Medical schools don’t care what you major in. They care whether you:

  • Crush the prerequisites
  • Do well on the MCAT
  • Show consistent, meaningful commitment to medicine

Your major is just the container. The contents—your GPA, MCAT, activities, and story—are what get you in.

(See also: How Many Clinical and Shadowing Hours Do I Really Need Before Applying? for more details.)

Let’s break down how to actually choose between biology, chemistry, or something else in a way that helps (not hurts) your med school chances.


What Medical Schools Actually Care About (Not Your Major)

Here’s the hierarchy of what matters for med school admissions:

  1. Science and overall GPA
  2. MCAT score
  3. Clinical experience, volunteering, and shadowing
  4. Consistency and depth in activities (leadership, research, service)
  5. Letters of recommendation
  6. Personal statement and interviews
  7. Your major (way below the others)

Medical schools routinely admit:

  • English majors
  • Economics majors
  • Engineering majors
  • Music and art majors
  • Public health, psychology, philosophy, computer science, you name it

As long as they’ve completed these common pre‑med prerequisites:

  • 1 year of general biology with lab
  • 1 year of general chemistry with lab
  • 1 year of organic chemistry with lab (some schools now accept biochem instead or in addition)
  • 1 semester–1 year of biochemistry
  • 1 year of physics with lab
  • 1–2 semesters of math (often stats + calc or just stats)
  • 1–2 semesters of English / writing
  • Sometimes: psychology and sociology (very helpful for MCAT)

The takeaway: Your major is not a requirement. Your prerequisites are.


Should You Major in Biology as a Pre‑Med?

Biology is the classic pre‑med major. It feels safe. Familiar. “Doctor = biology,” right?

Here’s the real breakdown.

Advantages of a Biology Major

  • Lots of overlap with pre‑med requirements
    Your major courses often fulfill med school prereqs (bio, some chem, sometimes biochem).

  • MCAT content alignment
    You’ll see a lot of MCAT biology, physiology, genetics, cell biology in your classes.

  • Easy to “tell the story”
    It’s simple to explain how your academic path relates to medicine.

  • Peers and advising often pre‑med oriented
    You’ll be surrounded by other pre‑meds and faculty used to writing letters for med school.

Disadvantages of a Biology Major

  • Crowded and competitive
    At many schools, biology is oversubscribed. Curved courses, lots of pre‑meds all gunning for A’s.

  • Can be GPA‑dangerous
    Certain required “weed‑out” classes (like genetics, cell bio, physiology) are famously tough.

  • Less academic differentiation
    On paper, you’ll look like thousands of other bio majors unless you’ve done something distinctive (research, leadership, special interest).

  • Limited built‑in backup plan
    A plain biology B.S. without additional skills can be less marketable if you don’t go straight to med school.

Who Biology Is Good For

  • You truly love biological sciences and can see yourself being excited about advanced classes.
  • Your school’s biology program has fair grading and good support, not brutal curves that tank GPAs.
  • You want straightforward MCAT alignment and aren’t as concerned about being “different” on paper.

If you pick biology, build in ways to stand out:

  • Do research with a specific focus (cancer biology, immunology, neuroscience).
  • Add a minor (e.g., statistics, public health, ethics, computer science).
  • Take upper‑division courses that both interest you and support your story (e.g., global health, genomics, medical microbiology).

Should You Major in Chemistry as a Pre‑Med?

Chemistry majors are less common than biology among pre‑meds, but they’re very respected academically.

Advantages of a Chemistry Major

  • Signals academic rigor
    Chem is known as a challenging major. Doing well in it makes a strong statement about your quantitative and analytical ability.

  • MCAT chemistry/physics strength
    You’ll be overprepared for gen chem and orgo sections, and you’ll handle biochem concepts more comfortably.

  • Smaller department, closer relationships
    Many chemistry departments are smaller than biology, which can mean stronger letters and better mentoring.

  • Good backup options
    You can pivot into industry (pharma, materials), teaching, or graduate school in chemistry if med school is delayed or not pursued.

Disadvantages of a Chemistry Major

  • Very time‑intensive
    Lots of lab hours, tough problem sets, and a course sequence that can crowd your schedule.

  • Less biology exposure by default
    You’ll need to intentionally add extra biology courses that both cover prerequisites and help with MCAT bio content.

  • Can be harshly graded
    In some programs, average exam scores are low and curves are unforgiving.

Who Chemistry Is Good For

  • You genuinely like chemistry and problem‑solving, not just tolerate it.
  • You’re okay with a heavy workload and long lab blocks.
  • You want a major that’s both rigorous and provides non‑med school options.

If you go this route:

  • Plan early how you’ll fit biology, physiology, and possibly psychology/sociology into your schedule.
  • Avoid overloading every semester with 3–4 hard STEM classes; protect your GPA.

When “Something Else” Is Actually the Best Pre‑Med Major

Here’s the part people don’t hear enough:
If you want the best shot at a high GPA and a unique application, a non‑biology/chemistry major can be an advantage.

Medical schools appreciate academic diversity. They like applicants who bring different lenses to medicine.

Strong Non‑Traditional Majors for Pre‑Meds

These work especially well when combined with the standard prereqs:

  • Public Health – Great for students interested in populations, health systems, disparities. Very medicine‑relevant.
  • Psychology – Lines up with MCAT psych/soc, useful for psychiatry, pediatrics, primary care.
  • Neuroscience – Hybrid bio/psych. Strong fit if you’re drawn to neurology, neurosurgery, psychiatry.
  • Biomedical Engineering – Good for tech‑minded students; shows quantitative strength (but can be GPA risk if your school grades tough).
  • Economics or Business – Interesting for future work in healthcare management, policy, or administration.
  • Philosophy or Ethics – Great for people interested in medical ethics, law, or deep reasoning.
  • English or History – Can make you an excellent communicator and writer, which helps on the MCAT CARS and in personal statements.
  • Computer Science / Data Science – Relevant to health tech, AI in medicine, bioinformatics, EMR systems.

Why These Can Be Powerful

  1. You’ll stand out
    “Biology major with hospital volunteering” is common.
    “Philosophy major researching medical ethics and working in a hospice” is not.

  2. You may protect your GPA
    If you’re naturally strong in writing, social sciences, or math, leaning into that can make straight A’s more attainable than slogging through classes you dislike.

  3. You can build a coherent narrative
    A public health major who works in community clinics and volunteers at a free health fair tells a very clear, compelling story about their interests.

The Catch

You still need to complete:

  • All required science prereqs
  • Enough upper‑division sciences to show you can handle rigorous coursework
  • Time to prep seriously for the MCAT

So you must plan your course sequence early with an advisor.


How to Actually Decide: A Simple Framework

Instead of “What do med schools want?” start with:

1. What classes do you genuinely enjoy and excel in?
Look at your past performance:

  • Loved AP Bio and did well → biology, neuroscience, or public health might make sense.
  • Loved AP Chem/Calc → chemistry, biochem, or engineering.
  • Loved APUSH, English, or debate → consider history, English, philosophy, or political science.

Your odds of a high GPA skyrocket when you’ll actually look forward to the work.

2. What’s your school’s culture and grading like in each major?

Ask older students:

  • Is the biology major overloaded with pre‑meds and brutal curves?
  • Is chemistry doable or soul‑crushing at your institution?
  • Which departments are known for good teaching and reasonable grading?

Don’t guess. Ask.

3. How flexible is the major with electives and scheduling?

Look for:

  • Room to fit your prereqs without 18–20 credit semesters every term
  • Ability to study abroad if you care about that
  • Capacity to add a minor (e.g., public health, stats, language)

4. What’s your backup plan if med school is delayed or doesn’t happen?

You don’t have to obsess over this, but at least consider:

  • Would you be okay working in research with a biology degree?
  • Would you like data analysis jobs with a stats or CS minor?
  • Would a public health degree open jobs you’d actually want?

You’re not jinxing anything by planning intelligently.


The Smartest Overall Strategy for Pre‑Med Majors

Here’s the approach that tends to work best:

  1. Major in something you’re good at and interested in
    Biology, chemistry, or something else. Interest + ability > “what most pre‑meds do.”

  2. Make sure your schedule supports a strong GPA
    Don’t cluster all killer courses in the same semester. Mix heavy STEM with lighter or non‑lab classes when possible.

  3. Layer your story on top of your major
    Whatever you pick, connect it to medicine through:

    • Volunteering and clinical experience
    • Research (if available)
    • Related electives
  4. Use electives and minors strategically
    Examples:

    • Bio major + statistics minor → better for research and evidence‑based medicine.
    • Psych major + biology minor → strong MCAT alignment and clear psych/medicine connection.
    • Engineering major + public health minor → tech + systems view of healthcare.
  5. Protect time for MCAT prep
    Don’t pack your hardest courses in the same semester you plan to study intensely for the MCAT. Plan around that 3–4 month window.


Common Pitfalls to Avoid

  • Choosing biology “because that’s what pre‑meds do” when you hate it. That’s a fast track to a mediocre GPA and burnout.

  • Assuming a “harder” major makes up for a lower GPA. It doesn’t. A 3.3 in chemical engineering doesn’t automatically beat a 3.8 in psychology. GPA still dominates.

  • Ignoring non‑science strengths. If you’re a gifted writer or communicator, lean into that. Medicine needs physicians who can explain, persuade, and connect.

  • Overloading on science every semester. One miserable 18‑credit, all‑STEM semester with B‑minus grades can do more damage than taking an extra term in school.


Quick Cheat Sheet: Biology vs Chemistry vs Something Else

  • Choose Biology if:

    • You’re genuinely excited by living systems
    • Your school’s program isn’t notorious for crushing pre‑med GPAs
    • You want straightforward MCAT and prereq alignment
  • Choose Chemistry if:

    • You like problem‑solving and don’t mind math‑heavy work
    • You’re okay with a lab‑intensive, rigorous curriculum
    • You want strong quantitative credentials and a solid backup path
  • Choose “Something Else” if:

    • You have clear non‑science academic strengths or passions
    • You’re willing to plan prereqs carefully
    • You want to stand out and build a distinct, coherent narrative

FAQ

1. Do medical schools prefer biology or chemistry majors?
No. They don’t have an inherent preference for biology over chemistry, or either over non‑science majors. They care far more about your GPA, MCAT, and evidence that you understand what a medical career involves. A 3.9 in history with strong science prereq grades is more attractive than a 3.4 in biology just because “it’s more common for pre‑meds.”

2. Is it harder to get into medical school with a non‑science major?
Not if you complete the prerequisites and do well. Many successful applicants are non‑science majors. What you must show is that you can handle rigorous science coursework (through your prereqs and a few upper‑division sciences) and that you’ve prepared for the MCAT. If anything, a strong non‑science major can help you stand out as long as your science grades are solid.

3. Will a biology or chemistry major make the MCAT easier?
They’ll make parts of it more familiar but not necessarily “easy.” Biology majors tend to feel more comfortable with MCAT bio/biochem content. Chemistry majors tend to feel strong on the chem/physics portion. Regardless of major, you still need dedicated MCAT prep. You’ll see topics (like psychology/sociology and test‑specific passage styles) that no major fully prepares you for.

4. What if I start as a biology major and later realize I hate it?
You can absolutely switch. Many students change majors once they see what college biology is really like. If that happens, talk to your advisor early. Map out:

  • How to still complete your pre‑med prerequisites
  • Whether a new major (e.g., psychology, public health, or something else) fits your interests better
    Medical schools don’t penalize you for changing majors. They care what you did with the time you had.

5. Does an “easier” major look bad to med schools if I’m just trying to get a high GPA?
No, assuming you’re not obviously gaming the system with the lightest possible course loads and no rigor. Choosing a major that matches your strengths is smart, not suspicious. Admissions committees understand that different students excel in different areas. You still need some challenging courses, strong science performance, and meaningful activities. But no one on a committee will say, “We can’t accept this applicant; they majored in sociology.”

6. Can I major in engineering and still be pre‑med?
Yes, but you need to be strategic. Engineering is time‑intensive and often harshly graded, so GPA risk is real. If you love engineering and can realistically maintain a strong GPA, it can be a great option, especially if you’re interested in tech, devices, or systems in healthcare. Just plan:

  • Which semesters you’ll take bio, chem, orgo, and physics
  • When you’ll study for the MCAT
  • How you’ll fit in clinical experiences with a heavy schedule

Bottom line:

  1. Major in something you like and can excel in—biology, chemistry, or anything else.
  2. Protect your GPA, complete your prereqs, and plan around the MCAT.
  3. Use your major to tell a coherent story about why you’re headed toward medicine, not to check some imaginary “pre‑med box.”
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