Essential SOAP Preparation Guide for DO Graduates in Nuclear Medicine

As a DO graduate interested in nuclear medicine, preparing strategically for the Supplemental Offer and Acceptance Program (SOAP) can turn a stressful week into an opportunity. Nuclear medicine is a small, niche specialty with a unique training pathway and relatively few positions, so planning specifically for a nuclear medicine match via SOAP is crucial.
This guide walks you step-by-step through SOAP preparation tailored to a DO graduate targeting nuclear medicine residency, with practical strategies you can start implementing months before Match Week.
Understanding SOAP and Its Role in the Nuclear Medicine Match
Before you can prepare effectively, you must be absolutely clear on what is SOAP, how it works, and how it interacts with the osteopathic residency match and nuclear medicine pathways.
What is SOAP?
The Supplemental Offer and Acceptance Program (SOAP) is the NRMP’s structured process that helps unmatched or partially matched applicants obtain unfilled residency positions during Match Week.
Key elements:
Who participates?
- Applicants who:
- Registered for the Main Residency Match
- Are eligible to start residency on July 1
- Are unmatched or partially matched by Monday of Match Week
- You must be SOAP-eligible (NRMP determines this and notifies you via email and in your NRMP account).
- Applicants who:
Timeline overview (approximate):
- Monday:
- 10:00 AM ET – You learn your match status.
- 11:00 AM ET – List of unfilled programs released in ERAS (SOAP-participating programs only).
- Monday–Thursday:
- Up to 45 SOAP applications total to programs.
- Programs review applications, conduct interviews (often virtual), and make offers in SOAP rounds (Monday–Thursday).
- Thursday afternoon:
- SOAP concludes, and remaining unfilled positions (if any) become visible to all.
- Monday:
Important rules:
- You cannot contact programs outside ERAS during SOAP. No cold calling or emailing PDs, coordinators, or faculty unless a program contacts you first.
- You cannot discuss positions with programs that are not participating in SOAP until SOAP ends Thursday.
How SOAP Relates to a DO Graduate and Osteopathic Residency Options
As a DO graduate, you navigate the same NRMP SOAP process as MD graduates since ACGME accreditation is now unified. However:
- Some programs remain more DO-friendly than others (historic DO acceptance, faculty with DO degrees, emphasis on holistic review).
- A few DO graduates may have participated in separate osteopathic-oriented pathways (e.g., military or specialty early matches), but the SOAP for ACGME programs is uniform.
Your SOAP strategy should combine:
- Nuclear medicine–focused options, and
- Backup specialties or transitional programs that keep doors open for a later nuclear medicine pathway.
Nuclear Medicine Residency Basics in the SOAP Context
Nuclear medicine is unique because:
- Many nuclear medicine pathways are post-residency fellowships after:
- Diagnostic radiology
- Internal medicine
- Other qualifying specialties (depending on board rules)
- There are also categorical nuclear medicine residency programs, but they are relatively few and may or may not participate in SOAP every year.
For SOAP planning, understand:
- Types of relevant positions you may see on the SOAP list:
- Categorical nuclear medicine residency (rare)
- Preliminary internal medicine or transitional year positions that keep nuclear medicine fellowship options open
- Occasionally, diagnostic radiology positions (more commonly competitive and less likely to appear in SOAP, but not impossible)
- Realistic goal for most DO graduates interested in nuclear medicine:
- Secure an ACGME-accredited PGY-1/PGY-2 spot in a field that preserves the path toward:
- Nuclear medicine fellowship
- Nuclear radiology fellowship
- Hybrid training opportunities (e.g., radiology with nuclear focus)
- Secure an ACGME-accredited PGY-1/PGY-2 spot in a field that preserves the path toward:
Pre–Match Week SOAP Preparation Strategy for DO Graduates
SOAP is fast and intense. The key is to do 80–90% of the work before Match Week.

Step 1: Clarify Your Nuclear Medicine Career Path
Nuclear medicine can be accessed via multiple routes. Before SOAP, decide:
Primary career vision:
- Long-term, do you see yourself as:
- A nuclear medicine specialist with broad clinical imaging responsibilities?
- A diagnostic radiologist with strong nuclear medicine skills?
- An internist with a niche in nuclear cardiology or PET imaging?
- Long-term, do you see yourself as:
Feasible entry point given your application strength:
- Board scores (COMLEX, USMLE if taken)
- Clinical grades and MSPE
- Nuclear medicine or radiology research
- Letters from imaging faculty
- Whether you already applied to:
- Radiology
- Internal medicine
- Nuclear medicine directly
- Transitional year or preliminary programs
Create a ranked list of realistic entry routes, for example:
- Categorical nuclear medicine residency (if any appear and you qualify)
- Diagnostic radiology categorical or advanced positions
- Internal medicine categorical positions
- Transitional year + later nuclear medicine fellowship
- Preliminary internal medicine + reapplication
This ranking will guide how you allocate your 45 SOAP applications.
Step 2: Build a “SOAP Playbook” Document
Before Match Week, create a single master document you can refer to under pressure. Include:
Personal narrative bullets:
- Why nuclear medicine?
- Osteopathic strengths: OMM understanding of anatomy, holistic care, patient-centered communication.
- Key experiences: nuclear medicine elective, radiology rotation, imaging-related QI project.
Three tailored 2–3 sentence “hooks”:
- One for nuclear medicine programs
- One for radiology / imaging-heavy fields
- One for internal medicine / transitional year programs
For example (nuclear medicine–focused hook):
As a DO graduate, my interest in nuclear medicine originates from seeing how functional imaging can personalize care for oncology patients during my PET/CT elective. I bring strong osteopathic training in whole-patient evaluation, which complements the precision of molecular imaging. I hope to develop expertise in theranostics and multidisciplinary oncologic care.
Updated CV bullets:
- Nuclear medicine–relevant rotations
- Any imaging research or QI
- Presentations or posters related to radiology, oncology, or imaging
Customized paragraphs you can drop into emails if contacted by programs (staying within SOAP rules)
This document will speed up your SOAP application customization and help you sound consistent and polished during interviews.
Step 3: Identify DO-Friendly and Nuclear Medicine–Relevant Programs
Weeks before Match Week:
Review your original application list:
- Which programs:
- Offered interviews?
- Were DO-friendly in past cycles?
- Had nuclear medicine divisions or strong imaging departments?
- Which programs:
Research potential target programs:
- Programs with:
- Nuclear medicine or nuclear radiology fellowships
- PET/CT, SPECT/CT, theranostics clinics
- Affiliation with cancer centers
- Even if they’re internal medicine or transitional year programs, the imaging environment matters for your networking and later fellowship prospects.
- Programs with:
For each potential backup specialty (IM, TY, prelim):
- Label them:
- High nuclear relevance (strong nuclear medicine presence)
- Moderate relevance (strong radiology department, some NM)
- Low relevance (still viable as a solid clinical base)
- Label them:
Keep this list handy. You won’t know in advance which programs will have unfilled spots, but if a program that appears on Monday also appears on your pre-made list, it becomes an immediate priority.
Step 4: Prepare SOAP-Specific Application Materials
Your base ERAS application is already submitted, but you can still:
- Update CV sections if allowed (check current year’s ERAS deadlines and rules).
- Prepare SOAP-specific personal statement variants:
- A nuclear medicine–focused statement (even if applying to IM or TY, this shows a clear career goal).
- A more general internal medicine / transitional statement emphasizing strong clinical training as a foundation for advanced imaging.
Each should be:
- 3/4 to 1 page
- Clearly state your identity as a DO graduate and what that adds:
- Training in OMM → deeper functional and structural understanding of the body
- Emphasis on preventive care and whole-person medicine
- Comfort with multidisciplinary, team-based care (vital for nuclear oncology boards, tumor boards, etc.)
Emphasize:
- Demonstrated interest in imaging or oncology
- Willingness to work hard in a smaller, subspecialized field
- Flexibility and resilience—critical qualities for anyone participating in SOAP
Step 5: Mental and Logistical Preparation
SOAP week is emotionally tough. Prepare in advance:
Technology:
- Reliable internet, backup hotspot
- Quiet space for virtual interviews
- Headset and camera tested
- Professional attire ready at hand
Schedule clearing:
- Inform preceptors or employers that Match Week may require quick scheduling changes.
- Protect Monday–Thursday as much as possible from conflicts.
Support system:
- Identify 1–2 mentors (ideally one in radiology or nuclear medicine) you can email for quick guidance.
- Let a trusted friend or family member know this week may be stressful.
Executing a High-Yield SOAP Strategy for Nuclear Medicine
When Monday of Match Week arrives and you learn you’re SOAP-eligible, you need a precise plan.
Step 1: Analyze the Unfilled Positions List Quickly and Rationally
At 11:00 AM ET Monday, the list of SOAP-participating unfilled programs appears in ERAS.
Filter and scan for:
Nuclear medicine residency positions
- These are rare, so if any appear and you are remotely competitive, they are priority targets.
Diagnostic radiology
- Advanced or categorical spots; typically competitive but worth scanning.
Internal medicine / transitional year / prelim IM at:
- Academic centers with nuclear medicine divisions
- Institutions known for strong imaging
Label each potential program:
- Tier 1: Nuclear medicine and diagnostic radiology positions
- Tier 2: Internal medicine / TY with strong imaging / nuclear presence
- Tier 3: Other IM / TY / prelim where you’d still get solid clinical training
Step 2: Allocate Your 45 SOAP Applications Strategically
With your tiered list, allocate applications with both ambition and realism:
If nuclear medicine residency spots are available:
- Apply to all that you reasonably qualify for (Tier 1).
- Then fill remaining slots with Tier 2 and Tier 3 programs.
If no nuclear medicine spots are available:
- Focus on internal medicine or TY programs that offer:
- Access to nuclear medicine electives
- Cancer center affiliations
- Radiology/nuclear mentors
- Focus on internal medicine or TY programs that offer:
A sample distribution might look like:
- 5–10 Tier 1 (if available; often fewer)
- 20–25 Tier 2 (IM/TY with strong imaging)
- Remaining as Tier 3 (IM/TY that still provide solid training and a path for reapplication)
Remember: your long-term nuclear medicine goal is preserved as long as you enter a qualifying core residency with strong clinical training and imaging access.
Step 3: Customize Communication for Nuclear Medicine–Relevant Programs
Though you can’t personally email programs during SOAP, your ERAS materials and interviews are your voice.
For programs with nuclear medicine relevance:
- Use your nuclear medicine–focused personal statement if possible.
- Highlight nuclear interests in your ERAS experiences:
- Imaging electives
- Cases where PET/CT changed management
- Any reading or self-study on theranostics, SPECT, PET/CT
During interviews, briefly connect your DO background to nuclear imaging:
My osteopathic training emphasized understanding how dysfunction develops in tissues and organ systems, which I find very complementary to nuclear medicine’s focus on physiologic and molecular processes. I’m particularly interested in how PET/CT and theranostic agents can individualize cancer care.
This shows the program you have a clear, coherent path—even if they’re an IM or TY program, they’ll see you as someone with a defined vision who will bring energy and focus to their institution.
Step 4: Prepare for Rapid-Fire SOAP Interviews
SOAP interviews are often short and scheduled with little notice. Be ready with concise answers to:
“Why did you go unmatched?”
- Focus on neutral, growth-oriented explanations:
- Late specialty switch
- Overly narrow specialty focus (e.g., applied mainly to radiology or nuclear medicine)
- Competitive specialty choice combined with geographic restrictions
- Avoid blaming individuals or systems.
- Focus on neutral, growth-oriented explanations:
“Why this program/this specialty?”
- For nuclear medicine or radiology:
- Emphasize your imaging interests and long-term specialty commitment.
- For IM/TY:
- Emphasize desire for strong clinical foundation and specific ways their program aligns with your nuclear goals (e.g., “nuclear medicine rotation,” “close collaboration with radiology”).
- For nuclear medicine or radiology:
“What strengths do you bring as a DO graduate?”
- Whole-patient perspective beneficial for interpreting imaging in clinical context
- Training in OMM → refined palpation and spatial reasoning about anatomy
- History-taking and physical exam skills → better correlation of imaging findings with clinical scenarios
Have a 20–30 second elevator pitch ready:
I’m a DO graduate with a strong interest in nuclear medicine and imaging, grounded in a holistic view of patient care. I completed rotations in radiology and oncology, where I saw how PET/CT and molecular imaging impact treatment decisions. I’m seeking a residency that will provide solid clinical training and imaging exposure so I can eventually pursue nuclear medicine and contribute to multidisciplinary cancer care.
Managing Emotions, Professionalism, and Backup Planning
SOAP can feel like a crisis, but for many, it becomes a critical turning point that still leads to satisfying careers in nuclear medicine.

Maintaining Professionalism and Composure
During SOAP:
- Respond quickly but calmly to interview requests.
- Keep answers brief, clear, and focused—programs are under time pressure too.
- Even if you feel disappointed, never show frustration or desperation to programs.
Remind yourself:
- Many successful physicians—radiologists, nuclear medicine specialists, internists—went through SOAP or reapplication cycles.
- Matching into a solid clinical program now can be a strategic bridge to your eventual nuclear medicine goal.
If You Don’t Receive a SOAP Offer
If SOAP ends without an offer:
Decompress briefly, but then quickly:
- Meet with your school’s advising office (if available).
- Seek guidance from a radiology or nuclear medicine mentor.
Explore options:
- Research or clinical positions in imaging or nuclear medicine departments
- Reapply next cycle with strengthened credentials:
- Additional imaging rotations
- Research or publications in nuclear medicine or oncology
- Improved personal statement, more targeted programs
Maintain engagement with nuclear medicine:
- Attend nuclear medicine conferences (e.g., SNMMI student/resident events)
- Join student/resident sections of imaging societies
- Read key nuclear medicine texts or review articles to deepen your foundation
Long-Term Perspective: Building Toward a Nuclear Medicine Career as a DO
Whether or not you match into nuclear medicine directly through SOAP, your long-term strategy is what ultimately defines your career trajectory.
Best-Case SOAP Outcomes for a Nuclear Medicine–Bound DO
Categorical nuclear medicine residency via SOAP
- Directly on your desired path.
- Focus on becoming excellent at:
- PET/CT, SPECT/CT
- Theranostics
- Oncologic and cardiac imaging
Internal medicine or transitional year in an academic center with strong nuclear medicine
- Maximize:
- Electives in nuclear medicine and radiology
- Research with nuclear medicine faculty
- Attendance at tumor boards, imaging conferences
- Then apply for:
- Nuclear medicine fellowship
- Nuclear radiology fellowship (via radiology > nuclear)
- Maximize:
Other but strong IM/TY/Prelim programs
- Excel clinically
- Seek out any imaging or oncology opportunities
- Network with nuclear medicine/radiology faculty
- Reapply with a stronger profile
Leveraging Your DO Background in Nuclear Medicine
As a DO graduate entering the nuclear medicine match pathway, you can highlight:
- Whole-person framework:
Understanding patient function and symptoms in relation to imaging findings. - Communication strengths:
Explaining complex imaging results to patients in accessible language. - Interdisciplinary mindset:
Comfort working with surgeons, oncologists, cardiologists, and radiologists—crucial for nuclear medicine tumor boards and multidisciplinary decisions.
Over time, these skills can make you a sought-after nuclear medicine physician, not just a technical expert in imaging.
FAQs: SOAP Preparation for DO Graduates in Nuclear Medicine
1. As a DO graduate, do I have a realistic chance at nuclear medicine through SOAP?
Yes, but you must be realistic and strategic. Direct nuclear medicine residency positions appearing in SOAP are uncommon, but they do exist some years. More commonly, DO graduates will:
- Match into internal medicine, transitional year, or prelim positions via SOAP; then
- Pursue a nuclear medicine fellowship afterward.
Your goal during SOAP is to secure a position that keeps the nuclear medicine pathway open—primarily IM or strong transitional programs, ideally at centers with robust nuclear medicine.
2. Should I focus my SOAP applications only on nuclear medicine and radiology programs?
No. Given the small number of nuclear medicine and radiology positions overall (and especially in SOAP), you should:
- Apply to any available and suitable nuclear medicine or radiology positions, but also
- Use most of your 45 applications on internal medicine and transitional year programs that:
- Are DO-friendly
- Have strong imaging or nuclear medicine departments
This balances ambition with a realistic chance of matching and preserves your nuclear medicine goals.
3. How can I highlight my interest in nuclear medicine when applying to internal medicine or transitional year programs during SOAP?
You can:
- Use a personal statement that:
- Emphasizes your goal of becoming a nuclear medicine specialist
- Explains how a strong IM/TY foundation will help you interpret imaging in clinical context
- During interviews, mention:
- Specific nuclear medicine experiences (electives, cases, research)
- Your plan to pursue nuclear medicine fellowship after core residency
- Ask about:
- Nuclear medicine rotations or electives
- Opportunities for imaging or oncology research
Programs appreciate applicants with a clear career direction, even if it’s in a subspecialty.
4. What is the most important SOAP preparation step for a DO graduate aiming at nuclear medicine?
The most important step is to prepare a thoughtful, tiered backup plan before Match Week:
- Know the nuclear medicine and imaging pathways you can enter via IM, TY, or other specialties.
- Pre-identify:
- DO-friendly programs
- Centers with strong nuclear medicine presence
- Prepare tailored personal statements, a polished nuclear medicine–focused narrative, and a logistical setup for rapid SOAP interviews.
With this preparation, SOAP becomes less about scrambling and more about executing a structured contingency plan that still leads toward your ultimate nuclear medicine career.
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